Given a permutation σ=σ1…σn in the symmetric group Sn, we say that σi matches the quadrant marked mesh pattern MMP(a,b,c,d) in σ if there are at least a points to the right of σi in σ which are greater than σi, at least b points to the left of σi in σ which are greater than σi, at least c points to the left of σi in σ which are smaller than σi, and at least d points to the right of σi in σ which are smaller than σi. Kitaev, Remmel, and Tiefenbruck systematically studied the distribution of the number of matches of MMP(a,b,c,d) in 132-avoiding permutations. The operation of reverse and complement on permutations allow one to translate their results to find the distribution of the number of MMP(a,b,c,d) matches in 231-avoiding, 213-avoiding, and 312-avoiding permutations. In this paper, we study the distribution of the number of matches of MMP(a,b,c,d) in 123-avoiding permutations. We provide explicit recurrence relations to enumerate our objects which can be used to give closed forms for the generating functions associated with such distributions. In many cases, we provide combinatorial explanations of the coefficients that appear in our generating functions.