A mixed dominating set is a collection of vertices and edges that dominates all vertices and edges of a graph. We study the complexity of exact and parameterized algorithms for \textsc{Mixed Dominating Set}, resolving some open questions. In particular, we settle the problem's complexity parameterized by treewidth and pathwidth by giving an algorithm running in time O∗(5tw) (improving the current best O∗(6tw)), as well as a lower bound showing that our algorithm cannot be improved under the Strong Exponential Time Hypothesis (SETH), even if parameterized by pathwidth (improving a lower bound of O∗((2−ε)pw)). Furthermore, by using a simple but so far overlooked observation on the structure of minimal solutions, we obtain branching algorithms which improve both the best known FPT algorithm for this problem, from O∗(4.172k) to O∗(3.510k), and the best known exponential-time exact algorithm, from O∗(2n) and exponential space, to O∗(1.912n) and polynomial space.