Given a proper edge coloring φ of a graph G, we define the palette SG(v,φ) of a vertex v∈V(G) as the set of all colors appearing on edges incident with v. The palette index ˇs(G) of G is the minimum number of distinct palettes occurring in a proper edge coloring of G. In this paper we give various upper and lower bounds on the palette index of G in terms of the vertex degrees of G, particularly for the case when G is a bipartite graph with small vertex degrees. Some of our results concern (a,b)-biregular graphs; that is, bipartite graphs where all vertices in one part have degree a and all vertices in the other part have degree b. We conjecture that if G is (a,b)-biregular, then ˇs(G)≤1+max, and we prove that this conjecture holds for several families of (a,b)-biregular graphs. Additionally, we characterize the graphs whose palette index equals the number of vertices.